A post shared by Ryan Santiago (@ryancsantiago) on May 15, 2016 at 3:45am PDT

MANILA - The second son of actor and singer Randy Santiago died from complications arising from multiple sclerosis, a statement from his family released Wednesday revealed.

According to the statement, Ryan, Santiago's son with wife Marilou Coronel, was diagnosed with the neurological disease for which there is currently no cure back in 2013. It damaged the protective covering of the nerves of his brain and resulted in him developing hydrocephalus.

Although he underwent a major brain surgery in an attempt to drain the fluids out, his health still further deteriorated.

"We find comfort in knowing that he is no longer in pain," said Santiago in the statement, in which he also described the passing of his 24-year-old son as deeply saddening.

According to medical websites, multiple sclerosis is a disabling neurological condition widespread among young people, but is generally considered rare in tropical countries like the Philippines.

Ryan passed away last Sunday. His death was mourned by some of his celebrity friends such as sisters Julia and Dani Barretto, and megastar Sharon Cuneta.

Dani said that she's going to miss Ryan for his "beautiful smile," while Cuneta added that he died far too young.

A post shared by Dani Barretto (@danibarretto) on Aug 15, 2017 at 2:32am PDT

A post shared by Sharon (@reallysharoncuneta) on Aug 15, 2017 at 3:14pm PDT

Below is the full statement from Randy Santiago released to Pep:

The whole Santiago family is deeply saddened to pass on the news that our son, brother and nephew Ryan Leonardo Coronel Santiago has met our Lord and Creator at 2:56 pm on August 13, 2017. We find comfort in knowing that he is no longer in pain.

He was diagnosed with multiple sclerosis in 2013 and suffered from demyelinating disease (damage of the protective covering of the nerves of the brain).

These led to a condition called hydrocephalus. He underwent a major brain surgery to insert shunts in order to drain the fluid out.

Given that a shunt is a foreign object, it could cause infections, which the doctors tried to address through medications.

His health started to deteriorate because of loss of appetite as a result of the medications.

Ryan was born on November 9, 1992 to Randy and Marilou Santiago.

He was a true-blooded Lasallian having gone to school at La Salle Green Hills from grade school to high school before going to college at College of St. Benilde.

He is survived by his parents, Randy and Marilou, and his brothers, Raphael and Raiko Santiago.

Even at a young age, his passion for the creative arts was evident just like his uncles and grandparents. He had a great fashion style, considered to be an influencer and was a blogger.

Ryan’s family and friends will sorely miss his infectious smile, humor, vibrant personality, humble demeanor and caring ways.