MANILA == If Wednesday's episode of "The Greatest Love" were summed up in a single frame, it would have to be that shot of Z (Joshua Garcia), hand over his mouth, trying to stop his tears from falling after learning that his grandmother Gloria (Sylvia Sanchez) is losing her mind to Alzheimer's.

He already knew it beforehand but personally seeing his beloved grandmother decline into early-onset of the terrible disease, he begins to grapple with a plethora of emotions.

Gloria's dementia started before this afternoon's episode, shown through a sequence where she forgot that she had sent a text message telling her children that she is dying. But her disease made a significant a leap on Wednesday after seeing her family break out into a heated argument in front of her.

Amanda (Dimples Romana), Gloria's eldest, threw a fit after seeing her mother happily celebrating her birthday when she had been panicking over her alarming text message. She had long resented Gloria, thinking that she, for the longest time, had been unfaithful to their father. She refused to believe that she was diagnosed with Alzheimer's, downplaying it as just another one of her lies.

But as the realization arrived, Amanda could only look in horror as Gloria asks her and her siblings who they were. The heart-wrenching scene gave great insight into what it is like to lose a loved one to Alzheimer's, as many netizens pointed out.

Our moms will always occupy the softest part in our hearts. 😭 #TGLTheDeepImpact

— OKayeNotes (@OKayeNotes) January 11, 2017

Sometimes what you need is just a good cry. #TGLTheDeepImpact

— Perk Philipps (@PerkPhilipps) January 11, 2017

You got my respect The Greatest Love cast and staffs. I'm glued to my seat. Acting is beyond compare. Lech. Iyak bes.😢

#TGLTheDeepImpact

— Vivien (@vivienjlx) January 11, 2017

#TGLTheDeepImpact
The only teleserye that doesn't have a loveteam to gain viewers and popularity. Only talent. Pure acting talent👍🏾

— Boracay Baby (@yourboracaybaby) January 11, 2017

Hands down, The Greatest Love is the best Teleserye out of all Teleseryes... Don't fight me, you know I'm right #TGLTheDeepImpact

— Mendel (@MendelOfficial) January 11, 2017

This teleserye should be on primetime bida. #TGLTheDeepImpact

— ZONYBOY (@zondazaaa) January 11, 2017

Sanchez was superb as Gloria, only needing a few lines, timely eye-twitches, and confused glances to capture the struggle of her character.

Likewise, Garcia, fresh off his acclaimed performance in "Vince & Kath & James," gave a moving portrayal of a teen finding it difficult to accept that one of their mother-figures is dying.

However, Romana trumped everyone as she was unafraid to show viewers a hot-headed, difficult, and stubborn daughter that refused to accept that her mother was losing her mind to a fault. Her emotionally wringing scene where she watches Gloria break down over her disease is a definite highlight.

You are amazing @DimplesRomana #TGLTheDeepImpact

— Jed Madela (@jedmadela) January 11, 2017

BEST TELESERYE, BEST CAST, BEST STAFF, BEST STORY, BEST ACTORS AND ACTRESS!!! 👏👏 #TGLTheDeepImpact

— Empi (@eyuuuhn) January 11, 2017

Directed by Mervyn Brondial and Paco Sta. Maria, 'The Greatest Love also stars Matt Evans, Arron Villaflor, and Andi Eigenmann. It airs weekdays after 'Doble Kara' as part of ABS-CBN's 'Kapamilya Gold.'